Chronic renal failure (cell therapy) major clinical manifestations

From chronic renal failure stage, the general renal decompensation no symptoms; GFR decreased to 50ml / min or less, serum creatinine increased to 177 umol / L (2mg / dl) or more, the patient developed fatigue, loss of appetite, nocturia more mild anemia and other symptoms; stage renal failure, serum creatinine increased to 442 umol / L (5mg / dl) or more, GFR decreased to 20ml / min or less, the patients had significant anemia, increase in serum phosphate, calcium decline, metabolic acidosis, water and electrolyte disorders; when uremia, GFR in 10ml / mi n or less, serum creatinine increased to 707 umol / L or more, significant acidosis occurs all symptoms, even coma. General symptoms of chronic renal failure can be divided into three areas:

1. Due to regulate water and electrolyte disturbance caused due to coma as hyponatremia, sodium retention caused by edema, reduce or disappear after treatment.

2. Due to cause endocrine dysfunction, such as anemia, hypertension, renal osteodystrophy and metastatic calcification, blood purification performance of these applications its effects are often not significant or partial improvement.

3. uremic symptoms: Because urinary toxins accumulate in the blood, can cause gastrointestinal, cardiovascular, central nervous system damage and so on, these clinical symptoms appear system disorders, can be alleviated by dialysis.

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