gout
Gout is due to the increase in purine metabolism leads to the formation of uric acid. Inherited factors, this is a cause of gout. Even patients with no family history, such as beer, seafood, organ meats and fondue long-term intake can also cause gout.
In the early stages, decreased clearance of uric acid can cause an increase in uric acid in the blood. In this case, the patient usually has no symptoms. However, when the blood uric acid level is too high, uric acid crystals accumulate in the distal end of the connector.
The clinical manifestations of gout
Acute attack of gout usually painful, red, heat, swelling and stiffness. In most cases, these symptoms may occur suddenly.
How gout uremia?
Arthritis and kidney disease is a major complication of gout. Because arthritis is painful, patients can easily feel it. However, the onset of kidney disease is dormant, so most gout patients can not get timely find nephropathy. If kidney disease is caused by gout, which is what we call the purine metabolism of uric acid nephropathy. According to clinical studies, 17% ~ 25% of patients with gout eventually lead to renal failure.
In the past, patients with gouty nephropathy typically accounts for 1% of patients on dialysis. However, this ratio gradually increases in recent years. In the next 10 years, experts predict that this proportion will increase to 50%.
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